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Case Series/Study
Wound #1 (2019): At VHT initiation, the wound measured 1.4 x 1.6 x 0.3 cm with an area of 2.24 cm² and volume of 0.672 cm³. After 4 weeks, the wound achieved a 45.98% reduction in area and a 64.88% reduction in volume. By 8 weeks, the wound showed a 64.29% reduction in area and a 76.19% reduction in volume, ultimately achieving 100% resolution after 46 treatments over 28 weeks These cases highlight VHT’s transformative potential in reversing chronic wound deterioration in complex diabetic cases. For this patient, who previously experienced treatment failures, VHT facilitated remarkable healing outcomes.
Wound #2 (2024): Initially measured 1.2 x 1.9 x 0.5 cm with bioburden and pale granulation tissue. After 4 weeks of VHT®, the wound achieved a 56.6% reduction in area and a 74.0% reduction in volume. At 7 weeks, the wound showed an 89.5% reduction in volume, measuring 0.6 x 1.0 x 0.2 cm, and is on track to fully resolve with continued treatment.
At baseline (day zero), a temperature gradient was observed between the wound and periwound areas, suggestive of a potential infection. The mean tissue oxygenation at the wound bed was 90% ± 14%, with a hypoxic area present (St2 < 39%). Following four weeks of treatment, the temperature gradient persisted, though wound bed oxygenation improved to 91% ± 11%, and the hypoxic area was no longer detectable. By six weeks, both the temperature gradient and hypoxic area had resolved, indicating positive healing trajectory.
Discussion: